Dr. Charania's scholarly endeavors in psychiatric-mental health nursing, particularly in major depression in women and self-management strategies, emerged from her clinical practice of working with Pakistani women. Her long term research goal is to develop knowledge and understanding of a variety of self-management strategies to manage recurrent major depression and test them across a variety of cultures, with the ultimate goal of developing comprehensive groups of culturally sensitive strategies that could be identified, offered, and applied while caring from women from diverse backgrounds in both in-patient and community clinical practices. In July 2018, she received an American Psychiatric Nurses Association grant to support her research titled "Arab American Women with Recurrent Depression: Self-management Strategies and Social Determinants". This research study is currently underway.