NCID-1117
Omolola Adefeso
Professor of Chemical Engineering and Biomedical Engineering and University Diversity and Social Transformation Professor
University of Michigan
Education/Degree:
1 Chemical and Biomolecular Engineering (University of Pennsylvania)
About
Omolola (Lola) Eniola-Adefeso is a Nigerian-American[1] Chemical Engineer and the University Diversity and Social Transformation Professor of Chemical Engineering, Biomedical Engineering, and Macromolecular Science and Engineering at the University of Michigan. Eniola-Adefeso is also a co-founder and chief scientific officer of Asalyxa Bio.[2] Her research looks to design biocompatible functional particles for targeted drug delivery.
Current Work
Lola Eniola-Adefeso's research interests:
Due to their high specific interaction with their counter-receptors and their carefully regulated expression (limit to inflammation), leukocyte-endothelium adhesion molecules (LECAM) are attractive molecules for vascular targeting in human diseases in which inflammation plays a role. Our research goal is to use knowledge of the cellular inflammatory response and blood flow dynamics to design bio-functionalized particles for targeted drug delivery and imaging.
Work in the lab is divided into 3 major groups:
Cell Adhesion and Migration – Cells of the immune system.
Our goal is to use in vitro experimental setups to understand the receptor-ligand interactions involved in leukocyte firm arrest and transmigration.
Design of polymeric cells for targeted drug delivery.
We are working on designing sophisticated leukocyte mimetics that can target therapeutics to diseased vasculature via multiple receptor-ligand interactions with applications in cardi